The field of drug delivery has undergone remarkable transformations in recent decades, driven by the need for more effective, targeted, and patient-compliant therapies. This book, A Basic Novel Drug Delivery Systems: Principles, Technologies, and Therapeutic Applications, is written to serve as a foundational resource for students, researchers, and professionals involved in pharmaceutical sciences and drug development. This book aims to introduce the fundamental concepts and modern approaches in novel drug delivery systems (NDDS), highlighting their principles, the technologies employed, and the therapeutic advantages they offer. By focusing on innovations such as nanoparticles, liposomes, ocuserts, transdermal systems, and targeted delivery platforms, this text provides a comprehensive view of the ever-evolving landscape of drug delivery. Each chapter is structured to offer theoretical clarity as well as practical insights, supplemented by illustrations, case studies, and up-to-date references. The content is tailored to benefit graduate and postgraduate students in pharmacy and pharmaceutical technology, while also serving as a reference for academics and industry professionals. I sincerely hope this book will enhance understanding and stimulate further research and innovation in the field of novel drug delivery systems.